Конечно можно. Строки сравниваются с помощью обычных операторов сравнения. Взгляните на примеры ниже:
>>> 'hexlet' < 'python'
True
# Так как буква h идёт раньше чем p
# соответственно hexlet меньше python
>>> 'hexlet' == 'Hexlet'
False
# При сравнении регистр символов имеет значение
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